https://nova.newcastle.edu.au/vital/access/ /manager/Index en-au 5 The effectiveness and safety of direct oral anticoagulants following lower limb fracture surgery: a systematic review and meta-analysis https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46701 P < 0.0001) and less pharmacologically attributable adverse events (Odds ratio 0.62; 95% confidence interval, 0.46–0.82; P = 0.0007). There was difference between DOACs and conventional VTE prophylaxis regarding mortality, PE, symptomatic deep vein thrombosis, or bleeding events. The results generally support the use of DOACs for VTE prophylaxis after nonelective lower limb fracture surgery, such after hip fracture. The results more strongly support the use of XaIs; however, more evidence is needed to fully assess DOACs' role in clinical practice. Level of Evidence: Therapeutic Level II. See Instructions for Authors for a complete description of levels of evidence.]]> Tue 29 Nov 2022 10:42:17 AEDT ]]> Hip fracture: nutritional supplements https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:6820 Sat 24 Mar 2018 07:44:08 AEDT ]]>